Hyperbaric Chamber vs Ozone Therapy

Slow recovery can take a toll on your sanity. You just want to get back to feeling like yourself again. Fortunately, there are plenty of ways to speed up the healing timeline - including hyperbaric oxygen therapy, or HBOT for short.

This approach involves a hyperbaric chamber, a pressurized environment that helps your body push more oxygen into cells and tissues where it’s needed most. It can be used after an injury, a surgery, or even just a tough workout.

Morelli Medical is your trusted retailer for hyperbaric chambers for sale. But, we’re commonly asked - is ozone therapy the SAME as hyperbaric oxygen therapy? Not at all. So, we put together this hyperbaric chamber vs ozone therapy comparison guide!

The short answer, though, is that ozone therapy introduces medical-grade ozone into the body to stimulate healing through controlled oxidative stress. Both have their place, but HBOT offers deeper, more targeted recovery for post-surgery healing, injury repair, and athletic performance.

You can learn more about ozone therapy vs hyperbaric chamber therapy below. Or, you can connect with our experts at Morelli Medical for personalized guidance towards the right modality right now!

Category	Hyperbaric Oxygen Therapy (HBOT)	Ozone Therapy
How It Works	User breathes oxygen-rich air in a pressurized chamber, increasing oxygen delivery to cells and tissues	Ozone is introduced via gas or liquid mediums to stimulate oxidative stress and immune response
Primary Use Cases	Post-surgical recovery, wound healing, inflammation reduction, neurological support	Immune modulation, infection management, detoxification support
Evidence Base	Supported by decades of clinical research	Mostly anecdotal and used in alternative practices
User Experience	Non-invasive and quiet; user rests in a sealed chamber for 60-90 minutes	May involve needles, IVs, gas insufflation, or topical bagging
Risk & Side Effects	Low risk with proper use	Risk of oxidative damage if not administered properly or dosed correctly
Access & Cost	Available in clinics and at home; higher upfront cost but long-term value	Found in wellness or integrative clinics; lower cost per session but recurring

How Does a Hyperbaric Chamber Work?

These chambers increase air pressure while supplying concentrated oxygen to speed up healing. The air we breathe under normal conditions is about 21% oxygen. But the combination of elevated pressure and high oxygen concentration means you’re breathing nearly 100% pure oxygen (or near-pure oxygen, depending on the setup in question).

As a result, your blood plasma can carry up to 15-20 times more oxygen than normal. That extra oxygen reaches areas with poor blood flow, supports faster healing, and reduces inflammation across the body.

Sessions typically last 60-90 minutes and can be done in a soft shell hyperbaric chamber or hard shell hyperbaric chamber depending on the pressure level needed. Users can read a book, listen to a podcast, or just chill out while they breathe in oxygen-rich air. Potential benefits:

Enhances tissue oxygenation for faster healing
Reduces swelling and inflammation
Supports post-surgical recovery
May improve energy levels and focus
Promotes circulation and cellular regeneration

From helping people bounce back from a concussion or TBI faster to supercharging recover rates after surgery, clearing out brain fog so you can focus better at work - the use cases for HBOT are diverse.

It has been used in clinical settings for a really long time, but has recently become more accessible for at-home use thanks to portable hyperbaric chambers, like those available here at Morelli Medical.

We’ll talk more about our lineup of machines in a moment. But first, we need to look at the other half of our hyperbaric chamber vs ozone therapy comparison.

How Does Ozone Therapy Work?

This approach uses medical-grade ozone gas (O₃), a molecule made up of three oxygen atoms. That’s a key distinction between ozone therapy vs hyperbaric chamber therapy. You’re not getting more oxygen in the bloodstream here.

Instead, small amounts of ozone are introduced either via injection, intravenous infusion, or insufflation depending on the treatment method. Ozone reacts with fluids and tissues inside the body to produce a mild oxidative stress. This, in turn, stimulates the body’s own healing systems, including antioxidant production and immune response.

It may be able to neutralize pathogens, support detoxification, and improve circulation. However, ozone therapy is not approved by the FDA for most medical uses. It’s actually a bit controversial. Nevertheless, you’ll probably hear about benefits like:

May support immune function
Can help neutralize certain bacteria and viruses
Used in some cases to reduce inflammation
An adjunct for chronic conditions like Lyme disease or autoimmune disorders

Ultimately, this makes it pretty easy to choose between hyperbaric chamber vs ozone therapy. They serve very different purposes. On that note, let’s clear the air on a question we see circulating online - is ozone therapy the same as hyperbaric oxygen therapy?

Is Ozone Therapy the Same as Hyperbaric Oxygen Therapy?

Not at all. Hyperbaric chambers use pressure to boost oxygen absorption into the body, while ozone therapy introduces a reactive form of oxygen to trigger a biological response. The only similarity, really, is that “oxygen” is involved in some form or another.

So, which is right for you - ozone therapy vs hyperbaric oxygen therapy?

Hyperbaric Chamber vs Ozone Therapy: Key Differences to Consider

Hyperbaric oxygen therapy and ozone therapy are often mentioned in the same breath (pun intended!) but they’re entirely different approaches to wellness.

In fact, one is really well accepted, while the other remains shrouded in skepticism and uncertainty. Here’s how they really stack up.

Delivery Method and Treatment Setting

HBOT involves sitting or lying in a sealed chamber where air pressure is increased to somewhere between 1.3 and 2.0 ATA. You’re breathing in pure or oxygen-rich air. This forces more oxygen into the bloodstream so it can reach damaged tissues and stimulate healing.

On the other hand, ozone therapy introduces ozone gas (O₃), which is a reactive form of oxygen, into the body. It goes about it differently, though. You can’t just breathe it in. Instead, you’ll use one of the four delivery methods below:

Autohemotherapy: Blood is drawn, mixed with ozone, and reinfused into the body.
Rectal or vaginal insufflation: Delivered into the rectum or vagina via catheter.
Ozonated saline IV: Ozone is dissolved in saline and administered through an IV drip.
Topical or limb bagging: The body part is enclosed in a bag filled with ozone gas for local treatment

Whatever the case, it’s a more intensive form of therapy. It’s not something you can do at home or on your own. That’s where HBOT has an advantage. It’s really easy to do from the comfort of your home without having to stick yourself with a needle or use a catheter!

What the Treatment Actually Does

The goal in HBOT is to increase oxygen concentration in blood plasma. Why? To boost circulation, accelerate healing, and reduce inflammation. It’s passive. You let the chamber do the work. All you have to do is breathe.

In contrast, ozone therapy works through oxidative stress. It’s essentially a controlled inflammatory response that’s believed to trigger immune system activity and kill off pathogens.

This is part of why it hasn’t been widely accepted into mainstream wellness just yet. It’s more of a biological stressor than a replenishing therapy like HBOT.

Evidence and Clinical Use Cases

This is one of the biggest and most significant differences between a hyperbaric chamber vs ozone therapy. HBOThas decades of peer-reviewed clinical research behind it. It’s FDA-approved (or cleared) for 14 medical conditions in the U.S., including:

Non-healing diabetic wounds
Radiation injury
Carbon monoxide poisoning
Air or gas embolism
Severe infections like necrotizing fasciitis

It’s also widely used off-label for post-surgical recovery, concussion, long COVID, and athletic performance. There’s a wealth of anecdotal evidence supporting its use for so many different applications. It all comes down to helping you recover faster.

Ozone therapy does have some research behind it, particularly in Europe and parts of Asia, suggesting it could help with chronic infections, autoimmune issues, or herniated discs. But the amount (and quality) of evidence is lacking. It’s not FDA-approved for any condition.

Safety, Side Effects, and Contraindications

HBOT is generally well-tolerated, especially at mild to moderate pressures. Really, the only reported side effect we’ve seen is ear pressure or sinus discomfort - kind of like what you’d feel in an airplane during takeoff.

Rare complications include oxygen toxicity and barotrauma, but these are extremely uncommon at therapeutic levels used in most chambers. The machines we sell at Morelli Medical are very safe when used as directed.

Ozone therapy carries more risk if not administered correctly. Ozone is a toxic gas when inhaled directly and can irritate airways, which is why nasal or oral administration isn’t an option as it is with HBOT.

It can actually cause more harm than good if not dosed properly. It must be performed by trained professionals. Even then, though, the lack of regulation in the US raises red flags.

Cost, Frequency, and Accessibility

Another important distinction between the hyperbaric chamber vs ozone therapy comes down to cost. Ozone therapy sessions are generally cheaper, ranging between $50 to $150 per treatment.

But you have to go really often to maintain results. There’s no element of convenience here, either, since you have to visit a clinical setting to get the treatment. This is where HBOT has an edge.

Yes, these machines can be more expensive to own (starting at $6,900), but they pay for themselves in the long run in the form of cost savings. Plus, you can use the machine at your leisure without having to leave home.

Clinics typically charge $100 to $250 per session, depending on pressure and location. But, why not bring the benefits of HBOT into your home today with the help of Morelli Medical?

Discover What HBOT Can Do For YOU at Morelli Medical Today!

Our goal at Morelli Medical is to guide you through choosing the right hyperbaric chamber for your needs, goals, and space. No sales pressure or gimmicks. Just honest advice to help you heal better on your terms.

Whether you're looking for a mild soft-shell unit for home recovery or a high-pressure, clinic-grade model, we carry trusted models from top brands like Macy Pan and OxyRevo. You can narrow it down based on pressure setting below:

Our team knows this equipment inside and out. We’re here to answer your questions, explain pressure ratings, walk you through setup, and help you find the best match based on how and where you plan to use it.

We also offer flexible financing options to make bringing HBOT home more manageable. What more could you ask for? Take the next step at Morelli Medical today and see for yourself what these machines can do for you!

“The customer support team over, at Morelli Medical truly went above and beyond! They had expertise and were so understanding and really guided me to the ideal chamber for my needs.” - Sarah

“I was new to hyperbaric chambers, but the Morelli Medical team guided me. Their patience and detailed explanations were much appreciated.” - Emma

“The team at Morelli Medical was incredibly responsive to my inquiries always providing detailed answers prior, to my purchase of the chamber. Which perfectly met all my requirements and expectations.” - Dr. Ashley W.

Wrapping Up Our Comparison of Ozone Therapy vs Hyperbaric Chamber

Hopefully this hyperbaric chamber vs ozone therapy comparison has left you with clarity on the differences between these two approaches. While both support healing and recovery, they operate through entirely different methods.

Ozone therapy relies on oxidative stimulation, often with less clinical consistency. On the other hand, HBOT delivers measurable benefits supported by a growing body of research. It’s non-invasive, highly customizable, and increasingly accessible for home use.

Our blog has similar comparisons between the hyperbaric chamber vs oxygen mask and hyperbaric chamber vs cryotherapy if you want to learn more. But whether you’re searching for the best hyperbaric chamber for home or something you can add to your clinic, look no further.

Explore top-rated hyperbaric chambers now at Morelli Medical. Talk to our team and get matched with the right unit for your needs today!